Candida parapsilosis sensu stricto has emerged as a major cause of healthcare-associated candidemia, with increasing reports of fluconazole resistance worldwide. This resistance is most commonly associated with amino acid substitutions in Erg11p, particularly Y132F; however, regional variation in resistance mechanisms and clonal dissemination remains not fully understood. This study investigated the molecular epidemiology and...

The aim of the present study was to evaluate the effects of dietary supplementation with the microalgae Nannochloropsis oculata and Phaeodactylum tricornutum , either separately or in combination, on growth performance, lipid profile, haematoimmunological parameters, and resistance to Edwardsiella tarda infection in Nile tilapia ( Oreochromis niloticus ). A total of 960 juvenile Nile tilapia (2.87 ± 0.68 g and 5.65 ± 0.16 cm)...

Respiratory diseases remain a major public health challenge in tropical coastal cities, where persistent heat-humidity interactions and climate variability shape population vulnerability. This study quantified associations between atmospheric conditions and respiratory hospitalizations in Maceió, Brazil, using a 20-years time series (2000–2019). Weekly hospitalization rates stratified by age (children 0–4 years, adults 5–59 ye...

Bacterial resistance constitutes one of the main threats to global public health, driving the search for therapeutic strategies capable of restoring the effectiveness of antimicrobials. Among the mechanisms involved, efflux pumps stand out, reducing the intracellular concentration of drugs and contributing to multidrug resistance. In this context, inhibitors of these pumps emerge as a promising approach, as they increase the i...

Aim We investigate the distribution of dispersal modes — endozoochory (via animal ingestion), synzoochory (via animal seed accumulation) and anemochory (via wind)—and seed mass of woody plants across Brazilian ecosystems, testing whether their relative abundance in local plant communities could be predicted by climate, edaphic factors and dispersal agents (e.g., the main vectors moving seeds). We expected climate to be the mai...

The search for greater profitability and sustainability in dairy cattle farming drives the adoption of different production strategies, especially on small farms. The objective of this study was to evaluate the bioeconomic efficiency of pasture-based dairy production systems on farms of up to 70 hectares in the Pre-Amazon region of Maranhão. Data were collected from 24 dairy farms between January and December 2024 through in-p...