Ureaplasma diversum is an opportunistic bovine pathogen associated with reproductive disorders, including infertility, granular vulvovaginitis, placentitis, and abortion; however, detailed descriptions of fetal osteoarticular lesions remain exceptionally uncommon. This report describes the gross, histopathological, and molecular findings of a bovine abortion associated with U. diversum infection presenting with concurrent pulm...

Background The Passiflora genus presents a representative variability of passion fruit species with food, pharmacological and ornamental potential. To understand this genetic variability, it is essential that genetic resources are well characterized for future use in breeding and conservation programs. The aim of this study was to investigate for the first time the diversity genetic and structure population of 88 Passiflora ge...

Background This study explored the effect of blackberry fruit extract (BFE) and metformin (Met) on biochemical markers, redox parameters, and the downstream insulin signaling pathway in a high-fat diet (HFD) + streptozotocin (STZ) induced Type 2 Diabetic Rat model. Methods The identification and quantification of cyanidin-3-glucoside by HPLC in the BFE revealed a concentration of 28.33 ± 0.05 mg/g of dry extract. For in vivo s...

Background Cardiovascular diseases are the leading cause of death worldwide. An important mechanism involved is the disruption in protein homeostasis by overactivation of the classical axis of the renin-angiotensin system. The counterregulatory axis counteracts these effects; however, the MrgD receptor has recently been described, and its effects are unknown. Thus, this study aims to evaluate the impact of MrgD deficiency on c...

Species of the genus Beauveria are widely used as biological control agents due to their ability to infect and kill a broad range of arthropod pests. Despite their agricultural importance, the genomic diversity underlying virulence and secondary metabolism across the genus remains uncharacterized. In this study, we performed a comprehensive phylogenomic and biosynthetic gene cluster (BGC) analysis of 322 high-quality Beauveria...

This study presents a genomic and epidemiological exploration of the omicron variant sublineages in Tocantins, Brazil. A total of 556 positive samples, obtained from individuals testing positive for SARS-CoV-2 between December 21, 2021, and June 30, 2023, underwent genome sequencing. Following RNA extraction, cDNA synthesis was executed, and a multiplexed PCR assay was employed for sequencing using the Oxford Nanopore MinION p...

The COVID-19 pandemic, caused by SARS-CoV-2, has resulted in millions of infections and deaths. Studies describing the pathophysiology and characterizing the outcome of the disease in specific populations, including those living with HIV, are necessary. There is no consensus on whether the disease worsens in immunosuppressed patients, which is considered a risk factor, or if immunosuppression might confer protection against cy...

Yeasts of the genus Candida are microorganisms of significant relevance in clinical practice, particularly within intensive care units, where they are classified as high-risk pathogens due to their impact on immunocompromised patients. Despite this, fungi frequently remain neglected in comparison to other infectious agents, and their ecological role, specifically concerning wildlife, remains underexplored. Historically, wild a...

Cetaceans are sentinels of marine ecosystem health and are increasingly exposed to protozoal pathogens. This study investigated the occurrence and molecular identity of Sarcocystidae protozoa in 159 stranded cetaceans representing 21 species along the Brazilian coast. Molecular analysis based on PCR amplification and sequencing of the sarcocystid internal transcribed spacer 1 (ITS1) region revealed infections in 14 individuals...