Freshwater mussels are widely used as bioindicators of aquatic contamination due to their high filtration capacity and ability to accumulate trace elements. However, their potential role in contaminant sequestration and environmental remediation remains poorly explored under natural exposure conditions. In this study, we investigated trace element bioaccumulation dynamics in the freshwater mussel Unio elongatulus (Pfeiffer, 18...

P2X receptors, a family of ATP-gated ion channels, are increasingly recognized as key contributors to the pathophysiology of major depressive disorder. Among them, P2X7 plays a central role in stress-induced neuroinflammation by driving microglial activation, inflammasome signaling, and downstream reductions in BDNF and neuroplasticity. Additional P2X subtypes, including P2X4, further modulate neuronal and glial communication...