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The phenotypic diversity between castes in social species has been associated with increased regulation of gene expression. while the regulatory role of transcription factors (TFs) in the social transitions of Hymenoptera (bees, ants and wasps) is well studied, it remains poorly explored in Blattodea (cockroaches and termites). By analysing three cockroach and five termite genomes, we show that while Blattodea share some conve...
Defining an ageing-related pathology, disease or syndrome: International Consensus StatementNARA Subscribed
Around the world, individuals are living longer, but an increased average lifespan does not always equate to an increased health span. With advancing age, the increased prevalence of ageing-related diseases can have a significant impact on health status, functional capacity and quality of life. It is therefore vital to develop comprehensive classification and staging systems for ageing-related pathologies, diseases and syndrom...
Purpose of Review The unique properties of per- and polyfluoroalkyl substances (PFASs) have seen their widespread adoption, subsequent accumulation in the environment and concern regarding potential environmental effects. Globally, airfields and paved firefighting training surfaces are hotspots for accumulation of PFAS due to extensive use of aqueous film-forming foams (AFFF). Evidence from contaminated concrete and asphalt ai...
More effective transposon regulation in fertile, long‐lived termite queens than in sterile workersNARA Subscribed
Transposable elements (TEs) are mobile genetic sequences, which can cause the accumulation of genomic damage in the lifetime of an organism. The regulation of TEs, for instance via the piRNA‐pathway, is an important mechanism to protect the integrity of genomes, especially in the germ‐line where mutations can be transmitted to offspring. In eusocial insects, soma and germ‐line are divided among worker and reproductive castes,...
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