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Barriers and facilitators to implementing the European code of cancer practice in a rural and coastal setting: a qualitative studyNARA Subscribed
Purpose The European Code of Cancer Practice (ECCP) is a patient-centred framework for good clinical cancer practice, to improve outcomes for all of Europe’s patients [1]. Given challenges with applications to rural regions, the study aimed to explore the barriers and facilitators to implementing the ECCP in a rural, coastal, and urban context. Methods We conducted semi-structured individual and group interviews with nine acut...
Targeted Analysis of Chondrocyte Central Metabolites in Response to Cyclical Compression and Shear DeformationsNARA Subscribed
Osteoarthritis results in deterioration of articular cartilage, the soft tissue covering articulating surfaces of bones in joints like the knee and hip. Cyclical mechanical stimulation of articular cartilage results in synthesis of cartilage matrix, suggesting that therapeutic mechanical stimulation might be beneficial for cartilage repair in osteoarthritis. Prior studies identify ion channels and cytoskeletal molecules as com...
HIV is highly comorbid with cocaine use disorder (CUD). Relapse is a major challenge in the treatment of CUD, and people living with HIV (PLWH) exhibit shorter time to relapse. One driver of relapse may be re-exposure to cocaine, which can be modeled in rodents using cocaine-primed reinstatement. This process involves neuroadaptations within the medial prefrontal cortex (mPFC) and nucleus accumbens (NAc) shell, regions that me...
Long‐term ocean warming impacts the marine environment, and these effects will be exacerbated by future climate change affecting, e.g., biogeochemical processes and microbial communities. However, how the sediment microbial cell abundance and live/dead ratio respond to warming is poorly understood. In this study, sediment core samples were collected from a Baltic Sea bay artificially heated on average 5°C for > 50 years above...
Purpose Rural communities frequently experience inequalities in cancer care compared to urban counterparts. Despite growing academic interest , there has been no global bibliometric analysis of rural cancer publications. Increasingly, global policies focus on place-based health inequalities; it is critical to understand the current state and emerging trends of rural cancer research. This analysis focuses on publication trends,...
Zooplankton are crucial for food webs and biogeochemical cycles. However, warming associated with climate change may alter their seasonal timing and reproductive strategies. This study investigated how long‐term warming impacted zooplankton (mainly copepods) phenology and overwintering strategies by comparing a Baltic Sea bay, heated by warm water discharge for more than 50 yr, with an unaffected control bay. Field observation...
Effects of Biodiversity Loss on Freshwater Ecosystem Functions Increase With the Number of StressorsNARA Subscribed
A multitude of anthropogenic stressors drive biodiversity loss and alter ecosystem functioning. Freshwaters, which contribute disproportionally to global biodiversity and biogeochemical cycles, are particularly threatened. Although the relationship between biodiversity and ecosystem functions (BEF) is generally well‐established, especially in terrestrial ecosystems, the role of multiple, co‐occurring stressors in modulating th...