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Streptococcus dysgalactiae From Farm‐Raised Channel Catfish in Mississippi, USA, With Notes on Fish‐Associated Group C S. dysgalactiaeNARA Subscribed
Lancefield serological group C Streptococcus dysgalactiae (GCSD) is an emerging cause of fish disease worldwide, largely associated with mariculture in Asia. In the United States (US), GCSD had been a pathogen of minimal concern for fish, but recent cases indicate a putative emergence in wild and cultured freshwater fish populations in the Americas. The current study discusses three novel cases of GCSD‐associated streptococcos...
Zinc on the edge—isotopic and geophysical evidence that cratonic edges control world-class shale-hosted zinc-lead depositsNARA Subscribed
The North Australian Zinc Belt is the largest zinc-lead province in the world, containing three of the ten largest known individual deposits (HYC, Hilton-George Fisher, and Mount Isa). The Northern Cordillera in North America is the second largest zinc-lead province, containing a further two of the world’s top ten deposits (Red Dog and Howards Pass). Despite this world-class endowment, exploration in both mineral provinces dur...
Evaluation of Edwardsiella piscicida basS and basR mutants as vaccine candidates in catfish against edwardsiellosisNARA Subscribed
Catfish farming is the largest aquaculture industry in the United States and an important economic driver in several southeastern states. Edwardsiella piscicida is a Gram‐negative pathogen associated with significant losses in catfish aquaculture. Several Gram‐negative bacteria use the BasS/BasR two‐component system (TCS) to adapt to environmental changes and the host immune system. Currently, the role of BasS/BasR system in E...
Purpose Cannabichromene (CBC) is a phytocannabinoid commonly found in cannabis, yet its acute post-dose pharmacokinetics (PK) have not been examined in humans. This is a secondary data analysis from a trial investigating Spectrum Yellow oil, an oral cannabis product used for medical purposes that contained 20 mg cannabidiol (CBD), 0.9 mg Δ 9 -tetrahydrocannabinol (THC), and 1.1 mg CBC, per 1 mL of oil. Methods Participants ( N...
Evolving immunogenicity assay performance expectations and a lack of harmonized anti-drug antibody validation testing and reporting tools have resulted in significant time spent by health authorities and sponsors on resolving filing queries. Following debate at the American Association of Pharmaceutical Sciences National Biotechnology Conference, a group was formed to address these gaps. Over the last 3 years, 44 members from...
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