Purpose Transcatheter aortic valve replacement (TAVR) is the standard treatment for patients with aortic diseases at high surgical risk. Transcatheter heart valve prostheses (THV) are inserted into the aortic valve, creating a new area between the native and artificial leaflets. This area, known as neo-sinus, increases the thrombogenicity of THVs. But there is a lack of testing methods that evaluate thrombogenicity in vitro. M...

Purpose Numerical hemolysis models rely on experimental data to fit parameters and predict hemolysis under various conditions. However, existing experiments often use few replicates per condition, leaving inherent variability largely unaddressed. This can lead to oversimplified models that fail to capture the true nature of hemolysis. Here, we quantify intra- and inter-donor variability at a single, well-defined shear stress a...