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PRIMED2 Preclinical Evidence Scoring Tool to Assess Readiness for Translation of Neuroprotection TherapiesNARA Subscribed
Many neuroprotective and other therapies for treatment of acute ischemic stroke have failed in translation to human studies, indicating a need for more rigorous, multidimensional quality assessment of the totality of preclinical evidence supporting a therapy prior to conducting human trials. A consensus panel of stroke preclinical model and human clinical trial experts assessed candidate items for the translational readiness s...
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