Bovine anaplasmosis and babesiosis are important tick-borne diseases associated with significant economic losses, although fetal infection and abortion are rarely described. This study reports a bovine abortion associated with co-infection by Anaplasma marginale , Babesia bovis and Babesia bigemina. in the Midwestern region of Brazil. Fetal necropsy was performed, followed by cytological, histopathological, immunohistochemical...

Introduction Numerous pharmacological classes of compounds have been explored as novel and efficacious alternatives to standard mu opioid agonist analgesics. We and others have described G-protein biased kappa opioid agonists as having potential utility as analgesics due to a lower propensity to produce sedation and dysphoria, which are thought to be mediated in large part through beta-arrestin signaling. Methods Here we compa...

Background and Aims Nitrogenous fertilizers provide a short-lived benefit to crops in agroecosystems, but stimulate nitrification and denitrification, processes that result in nitrate pollution, N 2 O production, and reduced soil fertility. Recent advances in plant microbiome science suggest that genetic variation in plants can modulate the composition and activity of rhizosphere N-cycling microorganisms. Here we attempted to...

Forest models are instrumental for understanding and projecting the impact of climate change on forests. A considerable number of forest models have been developed in the last decades. However, few systematic and comprehensive model comparisons have been performed in Europe that combine an evaluation of modelled carbon and water fluxes and forest structure. We evaluate 13 widely used, state‐of‐the‐art, stand‐scale forest model...