Purpose Unrecognized contraindications pose risks for adverse drug reactions, hospitalizations or death. Clinical decision support systems (CDSS) aim to mitigate medication-related harm, particularly originating from contraindications. However, many CDSS provide limited benefit, as they focus largely on singular risk situations such as drug-drug interactions and often generate alerts of limited clinical relevance. Comprehensiv...

Soils store large quantities of carbon in the subsoil (below 0.2 m depth) that is generally old and believed to be stabilized over centuries to millennia, which suggests that subsoil carbon sequestration (CS) can be used as a strategy for climate change mitigation. In this article, we review the main biophysical processes that contribute to carbon storage in subsoil and the main mathematical models used to represent these proc...