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NARA Subscribed1
Publisher
Springer Nature1
Journal
Familial Cancer1
Publication Year
20251
Mathilde Jalving results 1 · Newest (Page 1/1, per page 25)
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Author: Mathilde Jalving ×Clear All Filters
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Evaluation of BRCA1/2 testing rates in epithelial ovarian cancer patients: lessons learned from real-world clinical dataNARA Subscribed
Familial Cancer · 2025 · Vol. 24 · Issue 2 · Springer
Lieke Lanjouw; Claire J. H. Kramer; Arja ter Elst; Geertruida H. de Bock; Katja N. Gaarenstroom; Refika Yigit; Lieke P. V. Berger; Christi J. van Asperen; Sabrina Z. Commandeur-Jan; Dimas M. X. van der Hall; Mathilde Jalving; Marjolein J. Kagie; Nienke van der Stoep; Tom van Wezel; Marian J. E. Mourits; Tjalling Bosse; Joost Bart
Identification of somatic and germline BRCA1/2 pathogenic variants in epithelial ovarian cancer (EOC) patients is essential for determining poly-(ADP-ribose)-polymerase (PARP) inhibitor sensitivity and genetic predisposition. In the Netherlands, BRCA1/2 testing changed to a tumor-first approach to efficiently identify both somatic and germline pathogenic variants in all patients. Here, we performed an in-depth evaluation of th...
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