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High‐Throughput Sequencing in Aquaculture Disease Investigations: Challenges and Opportunities for ImplementationNARA Subscribed
The current generation of sequencing technologies can produce terabases of data with exceptional accuracy and speed, at a fraction of the cost of older methods. Despite this unprecedented power, adoption into aquaculture health management presents several challenges, including identifying where such capability may be optimally deployed. Here we synthesise discussions from a structured expert workshop held at the 2025 Aotearoa...
Focused ultrasound-mediated opening of the blood brain barrier for non-invasive drug delivery to the murine cerebellumNARA Subscribed
Background The blood brain barrier (BBB) limits effective treatment for cerebellar diseases. Region-specific parameterization and safety data for MRI-guided focused ultrasound (MRgFUS) BBB opening (BBBO) in the cerebellum are scarce. The goal of this study is to establish safety and feasibility of cerebellar BBBO for antibody delivery. Methods Mice received i.v. AF680 IgG and microbubbles immediately prior to sonication at 0.3...
Host identity shapes Endozoicomonas composition in coral microbiomes across depths and marine protected areas at Little Cayman IslandNARA Subscribed
The bacterial genus Endozoicomonas is prevalent and abundant in the microbiome of many corals, but the combination of environmental and host factors shaping its distribution remains uncertain. In this study, we used 16S rRNA gene sequencing to examine the distribution of Endozoicomonas across hard ( Porites astreoides , Montastraea cavernosa , Agaricia spp.) and soft coral ( Muricea spp., Gorgoniidae, Cladiellidae, Malacalcyon...
The dispersal of ectomycorrhizal (EM) fungi is typically characterized by an ecological dichotomy in which aboveground (epigeous) mushrooms disperse via wind and belowground (hypogeous) truffles disperse via animal-mediated movement. To assess whether hypogeous EM fungi may be dispersed by wind more often than generally recognized, we used high-throughput sequencing of paired spore trap and soil samples at eight sites across t...
The official 2024/25 Australian summer monsoon (ASM) onset occurred on 7 February, more than two weeks later than the previous record. Defined using Darwin winds, the official ASM typically arrives between mid-December and mid-January. Here, we investigate (1) why the ASM onset was record late, despite La Niña-like conditions, and (2) if the late ASM onset was consistent with other unofficial monsoon and rainy season onset def...
Modern biodiversity monitoring programs are designed to provide rapid assessments of trends in the abundance and distribution of keystone taxa and timely scientific insights for decision‐making. An important consideration when delivering this information to stakeholders is the quantification of uncertainty, which determines the robustness of detecting changes across habitats and regions. In coral reef science, sparse and fragm...
Global annual cropland dynamics 2015–2024NARA Subscribed
Occupational related heat stress exposure and heat-related symptoms among sugarcane workers in ThailandNARA Subscribed
Objective Thai sugarcane workers often work in very hot, humid conditions. This study investigated the effect of heat stress exposure on heat-related symptoms and severe heat-related symptoms associated with heat stroke in Thai sugarcane workers. Methods Sugarcane workers in Nakhon Sawan Province, Thailand, recruited during cooler and hotter months of 2023 provided information on demographics, health behaviours, working condit...
Chemicals in plastics differentially affect the transcriptome of MCF-7 breast cancer cellsNARA Subscribed
Humans are exposed to chemicals that leach from plastics, yet many remain data-poor and lack toxicological evaluation. High-throughput transcriptomics (HTTr) provides a scalable way to screen chemicals and generate mechanistic insights relevant to human health risk assessment. We applied HTTr in MCF-7 breast cancer cells to assess chemicals across several concentrations (0.001–50 µM) used in plastics and dyes. Transcriptomic p...
Baleen Whale Occurrence in the Waters Off Virginia and North Carolina, U.S.A. From 2001 to 2019NARA Subscribed
Eighteen years of visual survey and strandings data were used to describe baleen whale occurrence along the continental shelf of Virginia and North Carolina, U.S.A. This region experiences heavy anthropogenic use, which poses risks for mortality and injury to baleen whales. Between 2001 and 2019, six species of baleen whales were recorded, and whales occurred year‐round. The total number of (on‐ and off‐effort) sightings and s...
State of the UK Climate in 2025NARA Subscribed