In the United States, colorectal cancer (CRC) mortality rates are higher in African Americans compared to non-Hispanic whites, partly due to advanced stage cancer diagnosis. Timely CRC screening helps to increase CRC early detection and survival in this population. The objective of this monitoring study was to survey African American patients of Community Health Centers (CHC) in north Florida and to monitor CRC screening adher...

The environmental conditions experienced by marine invertebrate larvae can have carry-over effects on later life stage performance, affecting population dynamics. For crown-of-thorns sea stars (CoTS; Acanthaster spp.), the terrestrial runoff hypothesis (TRH) suggests that eutrophic runoff plumes boost larval phytoplankton food supply, increasing metamorphic success and seeding outbreaks. However, river plumes also decrease sal...

Nomlabofusp is a cell penetrant peptide-based recombinant fusion protein designed to enter cells and deliver human frataxin into the mitochondria of adults and children with Friedreich’s ataxia. In this article we present non-clinical studies evaluating the pharmacology of nomlabofusp, including in a murine striated muscle tissue frataxin knockout model of Friedreich’s ataxia. We demonstrate that subcutaneous administration of...

Ports in Aotearoa New Zealand have or are currently undergoing extensive infrastructure developments to accommodate the global trend in larger commercial vessels and cruise ships. With no national standards for underwater noise, Lyttelton Port Company is the first Aotearoa New Zealand port to undertake monitoring to assess pile-driving generated noise effects on local Hector’s dolphins, an endemic and nationally vulnerable spe...

Southeast Asia hosts more felid species than any other region and, although smaller (

Operational forecasts rely on accurate and timely observations and it is important that the ocean forecasting community demonstrates the impact of those observations to the observing community and its funders while providing feedback on requirements for the design of the ocean observing system. One way in which impact of new observations can be assessed is through Observing System Simulation Experiments (OSSEs). Various satell...

Information on tropical Asian vertebrates has traditionally been sparse, particularly when it comes to cryptic species inhabiting the dense forests of the region. Vertebrate populations are declining globally due to land‐use change and hunting, the latter frequently referred as “defaunation.” This is especially true in tropical Asia where there is extensive land‐use change and high human densities. Robust monitoring requires t...