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A Geometric Feature Tracking Approach for Noninvasive Patient-Specific Estimation of Leaflet Strain from 3D Images of Heart ValvesNARA Subscribed
Purpose: Valvular heart disease is prevalent and a major contributor to heart failure. Valve leaflet strain is a promising metric for evaluating the mechanics underlying the initiation and progression of valvular pathology. However, generalizable methods for noninvasively quantifying valvular strain from clinically acquired patient images remain limited. This study aims to develop a robust feature tracking framework that enabl...
Biomechanically Informed Image Registration for Patient-Specific Aortic Valve Strain AnalysisNARA Subscribed
Purpose Aortic valve (AV) biomechanics play a critical role in maintaining normal cardiac function. Pathological variations, particularly in bicuspid valves, alter leaflet loading, increase strain, and accelerate disease progression. Accurate patient-specific characterization of valve geometry and deformation is essential, but existing imaging and computational methods often fail to capture rapid valve motion, discontinuous de...
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