Insulin appears to exert salutary effects in the central nervous system (CNS). Thus, brain insulin resistance has been proposed to play a role in brain aging and dementia but is conceptually complex and unlikely to fit classic definitions established in peripheral tissues. Thus, we sought to characterize brain insulin responsiveness in young (4–5 months) and old (24 months) FBN male rats using a diverse set of assays to determ...

Three clearly defined abrupt cooling events (ACEs) can be observed within Greenland Interstadial (GI)‐1 in the Greenland ice‐core records. However, the spatial variation in amplitude and timing of these ACEs is poorly understood due to the paucity of well‐dated records with quantified temperature reconstructions. This study presents high‐resolution chironomid‐inferred July air temperature (T Jul ) and oxygen isotope (δ 18 O) r...

Latitudinal gradients in species interactions are widely cited as potential causes or consequences of global patterns of biodiversity. However, mechanistic studies documenting changes in interactions across broad geographic ranges are limited. We surveyed predation intensity on common prey (live amphipods and gastropods) in communities of eelgrass ( Zostera marina ) at 48 sites across its Northern Hemisphere range, encompassin...