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Parasites play a critical yet understudied role in Arctic ecosystems, particularly within key subsistence species such as Arctic char ( Salvelinus alpinus ). As the Arctic undergoes rapid climate-driven change, establishing baseline parasite biodiversity is essential for monitoring ecological shifts and anticipating emerging health and conservation concerns. This study provides the most comprehensive assessment to date of Arct...
Global annual cropland dynamics 2015–2024NARA Subscribed
Bottom‐tow gear fisheries (trawls and dredges) produce ~24 million mt of harvest annually, representing a globally important animal‐sourced food system. While many are currently sustainably managed, growing concern over the potential for ecosystem impacts from bottom‐tow gears has increased pressure to improve these fisheries. We assembled an international working group of > 30 contributors, including fishing industry particip...
Abalone in the genus Haliotis are economically important for aquaculture. Abalone naturally graze on macroalgae; however, they are increasingly fed formulated pellets that lack essential nutrients in aquaculture. Dietary supplements may increase abalone growth performance, immunity, survival, and market traits. Despite these advantages, there has been limited industry uptake, which can be influenced by a lack of formal evidenc...
Purpose The DANFLU-1 trial suggested lower incidence of hospitalizations for pneumonia and influenza, respiratory disease and all-cause mortality among older adults receiving high-dose (HD-IV) versus standard-dose (SD-IV) influenza vaccine. This study assessed the relative effectiveness of HD-IV versus SD-IV according to comorbidity in elderly individuals. Methods This was a post-hoc analysis of the DANFLU-1 randomized control...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
The Holocene history of Australia's climate is surprisingly poorly understood. This is, in part, because of the relatively weak forcing of Holocene climate versus that of the late Pleistocene. However, it is commonly suggested that eastern Australia dried during the mid‐ to late‐Holocene and that this was in response to increased activity in the El Niño–Southern Oscillation (ENSO), in particular, the intensification of the El...
Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout ( Salvelinus namaycush ) acclimatized to winter and summer temperatures to determine the extent to which they seasonally adjust cardiac thermal performance and adrenergic control. We...
Genetic methods for informing conservation and management of salmonids in the Pacific Northwest, USANARA Subscribed
The management of Pacific salmonids Oncorhynchus sp. is complex, requiring a balance between conserving imperilled natural‐origin stocks and mitigation for hydrosystem operations, including supporting fisheries, using hatchery‐origin stocks. To achieve these objectives, various types of data are used such as genetic information. Given the wide geographic distribution of salmonids and the numerous institutions involved in their...