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Purpose Patch-clamping is a foundational technique in electrophysiology that requires substantial training due to its complexity and resource-intensive nature. This study evaluates the effectiveness of an interactive patch-clamping simulation in improving accessibility, skill acquisition, and educational outcomes compared to traditional training methods. Methods A virtual simulation replicating key aspects of patch-clamping wa...
Fish and invertebrate communities show greater day–night partitioning on tropical than temperate reefsNARA Subscribed
Diel partitioning of animals within ecological communities is widely acknowledged, yet rarely quantified. Investigation of most ecological patterns and processes involves convenient daylight sampling, with little consideration of the contributions of nocturnal taxa, particularly in marine environments. Here we assess diel partitioning of reef faunal assemblages at a continental scale utilizing paired day and night visual censu...
Grazing management for soil carbon in Australia: A reviewNARA Subscribed
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
Globally, few precipitation records extend to the 18th century. The England Wales Precipitation (EWP) series is a notable exception with continuous monthly records from 1766. EWP has found widespread use across diverse fields of research including trend detection, evaluation of climate model simulations, as a proxy for mid‐latitude atmospheric circulation, a predictor in long‐term European gridded precipitation data sets, the...
Recent multivariate changes in the North Atlantic climate system, with a focus on 2005–2016NARA Subscribed
Major changes are occurring across the North Atlantic climate system, including in the atmosphere, ocean and cryosphere, and many observed changes are unprecedented in instrumental records. As the changes in the North Atlantic directly affect the climate and air quality of the surrounding continents, it is important to fully understand how and why the changes are taking place, not least to predict how the region will change in...
Motivation The BioTIME database contains raw data on species identities and abundances in ecological assemblages through time. These data enable users to calculate temporal trends in biodiversity within and amongst assemblages using a broad range of metrics. BioTIME is being developed as a community‐led open‐source database of biodiversity time series. Our goal is to accelerate and facilitate quantitative analysis of temporal...
Sedentary time and postmenopausal breast cancer incidenceNARA Subscribed
Gene expression plasticity evolves in response to colonization of freshwater lakes in threespine sticklebackNARA Subscribed
Phenotypic plasticity is predicted to facilitate individual survival and/or evolve in response to novel environments. Plasticity that facilitates survival should both permit colonization and act as a buffer against further evolution, with contemporary and derived forms predicted to be similarly plastic for a suite of traits. On the other hand, given the importance of plasticity in maintaining internal homeostasis, derived popu...
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