Digital twins offer a wide range of potential applications throughout the food supply chain, as demonstrated by the example of determining the suitability for human consumption of pre-packaged minced pork through AI-driven shelf-life assessment. As food business operators, official food control authorities and consumers are open to the use of new technology, there is currently no regulatory need for action regarding the use of...

Observations from the California Current System (CalCS) indicate that the long‐term trend in ocean acidification (OA) and the naturally occurring corrosive conditions for the CaCO 3 mineral aragonite (saturation state Ω Ω falls below 1.5. Here, we quantify the impact of low Ω conditions on pteropods using an individual‐based model (IBM) with life‐stage‐specific mortality, growth, and behavior in a high‐resolution regional hind...

As a result of climate change, rockfalls and rock avalanches as well as landslides lead to an increasing hazard for settlement areas and infrastructures. The hazards of such mass movements mean that numerous protective structures must be planned and built. In addition to building such constructions, the refurbishment of existing protective structures is also playing an increasingly important role. Some of these protective stru...

Climate change, biodiversity loss, and chemical pollution are planetary‐scale emergencies requiring urgent mitigation actions. As these “triple crises” are deeply interlinked, they need to be tackled in an integrative manner. However, while climate change and biodiversity are often studied together, chemical pollution as a global change factor contributing to worldwide biodiversity loss has received much less attention in biod...

Most patients with congenital anomalies of the kidney and urinary tract (CAKUT) remain genetically unexplained. In search of novel genes associated with CAKUT in humans, we applied whole-exome sequencing in a patient with kidney, anorectal, spinal, and brain anomalies, and identified a rare heterozygous missense variant in the DACT1 (dishevelled binding antagonist of beta catenin 1) gene encoding a cytoplasmic WNT signaling me...

A new and uniquely structured matrix of mammalian phenotypes, MaTrics ( Ma mmalian Tr aits for Comparative Genom ics ) in a digital form is presented. By focussing on mammalian species for which genome assemblies are available, MaTrics provides an interface between mammalogy and comparative genomics. MaTrics was developed within a project aimed to find genetic causes of phenotypic traits of mammals using Forward Genomics. This...

In 2019, the EPMA celebrated its 10th anniversary at the 5th World Congress in Pilsen, Czech Republic. The history of the International Professional Network dedicated to Predictive, Preventive and Personalised Medicine (PPPM / 3PM) is rich in achievements. Facing the coronavirus COVID-19 pandemic it is getting evident globally that the predictive approach, targeted prevention and personalisation of medical services is the opti...

Ocean warming has been implicated in the observed decline of oceanic phytoplankton biomass. Some studies suggest a physical pathway of warming via stratification and nutrient flux, and others a biological effect on plankton metabolic rates; yet the relative strength and possible interaction of these mechanisms remains unknown. Here, we implement projections from a global circulation model in a mesocosm experiment to examine bo...

Summary Besides the ‘classical’ animals known as reservoirs for Salmonella spp., like poultry and cattle, reptiles have emerged as a significant source of human salmonellae infections during the last years. Reptile‐associated salmonellae frequently cause severe clinical courses including fatalities due to septicaemia and meningitis. Therefore, it is of major priority to develop measures which may help preventing cases of repti...