Maxime Mathieu results 24
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Peripheral microRNA signature in genetic frontotemporal dementia—findings from the GENFI initiativeNARA Subscribed
Frontotemporal dementia (FTD) is a neurodegenerative disease characterized by significant clinical and genetic heterogeneity, with approximately 40% of cases linked to hereditary genetic mutations, including MAPT , GRN , and C9ORF72 . Recently, microRNAs (miRNAs) have emerged as key regulators of cellular processes related to neurodegeneration and as potential biomarkers for FTD. However, their relevance in presymptomatic stag...
Open Questions on Ion–Neutral Collisions and Coupling in the Lower Thermosphere–Ionosphere: Electrodynamics, Energetics and DynamicsNARA Subscribed
The Lower Thermosphere–Ionosphere (LTI) is the interface region between the Earth’s atmosphere and space. It is modulated by the energy and momentum deposition from the magnetosphere above and by the impacting waves from the lower atmosphere. The LTI region is defined by the co-existence and interaction of neutral and ionized species within the region’s electric and magnetic fields. This interplay results in unique and complex...
Unresolved Questions in Subauroral Science: Exploring Key Challenges in Physics and ChemistryNARA Subscribed
The subauroral region, located equatorward of the auroral oval, is a highly dynamic and complex interface between the magnetosphere, ionosphere, and thermosphere. While traditionally associated with stable optical structures such as stable auroral red arcs, recent observations have revealed a wide range of transient and extreme phenomena—such as subauroral ion drifts and strong thermal emission velocity enhancement—which highl...
Citizen science (also referred to as participatory science or community science), in which members of the general public contribute to scientific research, is not a new concept, as early examples of such studies can be found a couple of centuries ago. With the advancement of technology in an increasingly connected world, it has never been easier to engage citizen scientists in research projects. In this paper, we review citize...
Do nanoplastics impact Pb up-taking by Hordeum vulgare L.?NARA Subscribed
Aims Root hairs are important for uptake, especially for nutrients with low mobility in soils with high sorption capacity. Mutants with defective root hairs are expected to have lower nutrient uptake, unless they compensate with more root growth. Since root hairs can also contribute to the plant's water uptake their importance could change over the course of a growing season. It was our objective to investigate the role of roo...
Extreme droughts are expected to increase in frequency and severity in many regions of the world, threatening multiple ecosystem services provided by forests. Effective strategies to adapt forests to such droughts require comprehensive information on the effects and importance of the factors influencing forest resistance and resilience. We used a unique combination of inventory and dendrochronological data from a long‐term (>3...
Pelagic production and the recruitment of juvenile polar cod Boreogadus saida in Canadian Arctic seasNARA Subscribed
Previous work found that an earlier ice breakup favors the recruitment of juvenile polar cod ( Boreogadus saida ) by enabling early hatchers to survive and reach a large size by late summer thanks to a long growth season. We tested the hypothesis that, in addition to a long growth season, an earlier ice breakup provides superior feeding conditions for young polar cod by enhancing microalgal and zooplankton production over the...
Growth and resilience responses of Scots pine to extreme droughts across Europe depend on predrought growth conditionsNARA Subscribed
Global climate change is expected to further raise the frequency and severity of extreme events, such as droughts. The effects of extreme droughts on trees are difficult to disentangle given the inherent complexity of drought events (frequency, severity, duration, and timing during the growing season). Besides, drought effects might be modulated by trees’ phenotypic variability, which is, in turn, affected by long‐term local s...
Contrasting resistance and resilience to extreme drought and late spring frost in five major European tree speciesNARA Subscribed
Extreme climate events (ECEs) such as severe droughts, heat waves, and late spring frosts are rare but exert a paramount role in shaping tree species distributions. The frequency of such ECEs is expected to increase with climate warming, threatening the sustainability of temperate forests. Here, we analyzed 2,844 tree‐ring width series of five dominant European tree species from 104 Swiss sites ranging from 400 to 2,200 m a.s....
Estimation of population allele frequencies from next‐generation sequencing data: pool‐versus individual‐based genotypingNARA Subscribed
Molecular markers produced by next‐generation sequencing ( NGS ) technologies are revolutionizing genetic research. However, the costs of analysing large numbers of individual genomes remain prohibitive for most population genetics studies. Here, we present results based on mathematical derivations showing that, under many realistic experimental designs, NGS of DNA pools from diploid individuals allows to estimate the allele f...
The palaeontological site of Venta Micena (Orce, Andalusia, Spain) lies in the eastern sector of the Guadix–Baza basin, one of the best documented areas in Europe for Plio‐Pleistocene biostratigraphy. The combination of biochronological and palaeomagnetic results, combined with the radiometric data obtained for Atapuerca Sima del Elefante, indicated that the Venta Micena stratum was formed between the Jaramillo and Olduvai pal...
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