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A brain-constrained neural model of cognition and language with NEST: transitioning from the Felix frameworkNARA Subscribed
We introduce a brain-constrained neurocomputational model designed to simulate higher cognitive functions of the human brain, implemented using NEST, a widely used open-source simulator optimised for high-performance spiking neural network simulations. Previously implemented in the custom-built C-based Felix simulation library, transitioning the model to NEST enhances accessibility, reproducibility, and computational efficienc...
The safety of using ethanol-based products for hygienic hand disinfection in healthcare workers is controlled by restricting air levels. This raises the question of whether these workers are sufficiently protected against potential dermal absorption. The study aim was to determine the contribution of the dermal route to the total uptake of ethanol. A laboratory-controlled study of 25 sequential alcohol-based-hand-rubs (ABHRs)...
Cladoceran diversity build-up in newly created pondscapesNARA Subscribed
Pondscapes, networks of closely situated ponds within a landscape, can provide important habitat for freshwater biodiversity and are increasingly considered to be valuable elements in nature restoration. Understanding how communities build up in newly created pondscapes is important for improving pond creation as a restoration tool. This study aimed to identify the main drivers of cladoceran species richness build-up and speci...
Climate‐driven changes in extreme precipitation and floods severely impact societies and ecosystems, yet regional spatial and temporal nuances remain poorly understood, including in the Hawaiian Islands. This study utilised stationary and non‐stationary Generalised Extreme Value (GEV) distributions, annual maximum series (AMS), and circular analysis to examine extreme hourly rainfall across 117 gauges on the five most populate...
Seafloor massive sulphide (SMS) deposits are potential sources of Cu, Zn, Au and Ag, however, how seafloor weathering affects the content of these metals in the deposits remains poorly understood. Key sulphide weathering products, i.e. Fe-oxyhydroxide and atacamite, can provide insight into metal mobilisation during and after oxidation of sulphides. Ten Fe-oxyhydroxide and three massive sulphide samples from the Semenov hydrot...
Peripheral microRNA signature in genetic frontotemporal dementia—findings from the GENFI initiativeNARA Subscribed
Frontotemporal dementia (FTD) is a neurodegenerative disease characterized by significant clinical and genetic heterogeneity, with approximately 40% of cases linked to hereditary genetic mutations, including MAPT , GRN , and C9ORF72 . Recently, microRNAs (miRNAs) have emerged as key regulators of cellular processes related to neurodegeneration and as potential biomarkers for FTD. However, their relevance in presymptomatic stag...
In 2023, more than half of olive harvests ( Olea europaea ) across Spain, Greece, and Türkiye were lost to drought. The same year late freeze destroyed 90% of the peach crop ( Prunus persica ) on the Georgia Piedmont and the apple crop ( Malus domestica ) in central New York, Vermont, and southern Quebec. Climate extremes now rank with the costliest threats to agriculture, but their role in forest recovery from diebacks that a...