Central Asia (CA) is among the world's most vulnerable regions to climate change. Increasing anthropogenic greenhouse gas concentrations (GHGs) are the primary forcing of the current and future climate system for the time scale of a century. By analysing observation datasets, we show that a warming of 1.2°C led to a decrease of 20% in snow‐depth CA during the last 70 years, especially over the mountains. In recent decades, lon...

Background Coumarins are an important class of widely distributed heterocyclic natural products exhibiting a broad pharmacological profile. In this work, a new series of coumarins bearing substituted 3,4-dihydro-2 H -benzothiazines were described as potential analgesic agents. The clinical use of NSAIDs as traditional analgesics is associated with side effects such as gastrointestinal lesions and nephrotoxicity. Therefore, the...