Hibernation is a physiological strategy animals use to survive in hostile environments with extreme temperature challenges and food scarcity. During this state, significant changes occur in metabolism and cellular function, with numerous stress response pathways recalibrated to survive physiological challenges that could otherwise be fatal. Numerous studies were performed to explain the molecular mechanisms of mammalian hibern...

Introduction Sea cucumbers are cultivated mainly for their valuable body wall. Polybrominated diphenyl ethers are common persistent pollutants in sea waters with known impacts on aquatic animals nonetheless not yet studied for the body wall of sea cucumbers. Methods Using ltra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-Triple-TOF-MS), we investigated the metabolic impact of 2,2',4,...