Hibernation is a physiological strategy animals use to survive in hostile environments with extreme temperature challenges and food scarcity. During this state, significant changes occur in metabolism and cellular function, with numerous stress response pathways recalibrated to survive physiological challenges that could otherwise be fatal. Numerous studies were performed to explain the molecular mechanisms of mammalian hibern...

Butylparaben (BuP) is a ubiquitous preservative in cosmetics, foods, and medicine. As an emerging pollutant, it has gained wide attention in recent years. Because amphibians have both aquatic and terrestrial life stages and high skin permeability, they are sensitive to environmental changes. To assess the toxic effects of BuP on amphibians, the present study was conducted on the spot-legged tree frog ( Polypedates megacephalus...