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This study identifies amide proton transfer (APT) imaging radiomic features that correlate with glioblastoma survival and explore the relationship of combined radiomic data and biomarkers such as age and MGMT methylation status to survival prognosis. In a retrospective study of 66 glioblastoma patients (2022–2023), SlicerBrats was used for automatic tumor segmentation and 504 radiomic features were extracted from APT images. A...
Class switched bovine ultralong CDR H3 amplicons versus canonical in immune and non-immune tissuesNARA Subscribed
Within the bovine immune response, a distinct type of immunoglobulin (Ig), known as ultralong complementarity-determining region 3 (CDR3) antibodies, coexists alongside canonical Igs. These ultralong heavy chains (HC) feature a remarkable structure with a lengthened CDR3 of the heavy chain (CDR H3), allowing them to adopt either a smaller and more extended paratope than canonical antibodies. However, very little is known about...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Size, growth, and density data for shallow‐water sea urchins from Mexico to the Aleutian Islands, Alaska, 1956–2016NARA Subscribed
Size, growth, and density have been studied for North American Pacific coast sea urchins Strongylocentrotus purpuratus , S. droebachiensis, S. polyacanthus , Mesocentrotus (Strongylocentrotus) franciscanus , Lytechinus pictus , Centrostephanus coronatus , and Arbacia stellata by various workers at diverse sites and for varying lengths of time from 1956 to present. Numerous peer‐reviewed publications have used some of these dat...
We examined polymorphism at seven microsatellite loci among sea trout ( Salmo trutta ) ( n = 846) collected from three areas in the Limfjord (Denmark). We then assessed their potential population source by comparing, using a mixed stock analysis (MSA) Bayesian framework, their genetic composition to that of brown trout collected from 32 tributaries pooled into nine geographical regions ( n = 3801) and two hatcheries ( n = 222)...
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