Ming-Cheng Luo results 129
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We herein constructed a phylogeny of Lepidoptera synthesizing multiple information types, a phylogenomics backbone, a multigene supermatrix with species‐comprehensive DNA barcodes, and topological information from a compiled database of standardized machine‐readable trees from over 100 previous studies. We then applied the new phylogenetic synthesis as a profiling framework for a large DNA barcode dataset of caterpillars from...
Temporal transcriptomic profiling identifies core regulators in cytokine-induced gut barrier disruption in differentiated Caco-2 cellsNARA Subscribed
Objective The intestinal epithelial barrier maintains gut homeostasis, and its disruption contributes to inflammatory diseases such as Inflammatory Bowel Diseases (IBD). Although barrier restoration is a promising therapeutic strategy, most current approaches target immune responses rather than epithelial function. Since barrier injury and repair progress through discrete phases, this study aimed to define time-resolved epithe...
Histamine can damage the antioxidant and immune systems in fish and crustaceans. Rutin, a natural substance with a diverse phenolic structure, has demonstrated antioxidant and anti-inflammatory properties. However, whether rutin can mitigate histamine-induced negative effects remains uninvestigated in fish models. This study investigated the effect of 0.1–100 μM rutin preincubation on histamine (29.5 mM)-induced cytotoxicity i...
Epigenetics in the modern era of crop improvementsNARA Subscribed
Epigenetic mechanisms are integral to plant growth, development, and adaptation to environmental stimuli. Over the past two decades, our comprehension of these complex regulatory processes has expanded remarkably, producing a substantial body of knowledge on both locus-specific mechanisms and genome-wide regulatory patterns. Studies initially grounded in the model plant Arabidopsis have been broadened to encompass a diverse ar...