In 2021, Taiwan experienced its most severe drought in 56 years, resulting in substantial crop losses, estimated to be approximately NT$1.65 billion due to insufficient water in reservoirs. This study employed the pseudo‐global‐warming method to project changes in seasonal rainfall during future droughts in northern Taiwan using a high‐resolution (1 km) regional mesoscale model. The simulation was based on the severe drought e...

Endozoicomonas is an omnipresent marine bacterial genus, associated with various marine organisms, that contributes to host health, nutrient cycling and disease resistance. Nonetheless, its genomic features remain poorly characterised due to a paucity of high‐quality genomes. In this study, we sequenced 5 novel Endozoicomonas strains and re‐sequenced 1 known strain to improve genomic resolution. By integrating these 6 high‐qua...

Background Infections caused by Klebsiella pneumoniae are common and result in high mortality rates. In vitro studies demonstrated the potency of cefoperazone/sulbactam (CPZ/SUL) against Klebsiella pneumoniae . However, the clinical efficacy of CPZ/SUL for the treatment of K. pneumoniae bacteremia has not been studied. Objectives This study aimed to associate the clinical outcomes of patients with bacteremia with the minimal i...

Expansion of the GGGGCC-RNA repeat is a known cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), which currently have no cure. Recent studies have indicated the activation of Sigma-1 receptor plays an important role in providing neuroprotection, especially in ALS and Alzheimer’s disease. Nevertheless, the mechanisms underlying Sigma-1R activation and its effect on (G 4 C 2 )n-RNA-induced cell death...