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Alzheimer’s disease (AD) is characterized by the buildup of extracellular aggregated amyloid-β (Aβ) peptides, following sequential enzymatic cleavage of amyloid precursor protein, along with intraneuronal accumulation of hyperphosphorylated Tau proteins and subsequent neuronal loss. Despite extensive research, the precise mechanisms underlying Aβ and Tau-mediated neurodegeneration remain elusive. Inhibiting protein aggregation...
Floods and fires are part of the ecological regime in many wetlands, yet their interconnectedness is poorly explored. Climate extremes, such as droughts and heatwaves, are increasing fire frequency and intensity, while changing rainfall patterns make floods more unpredictable. These events shape wetland physiognomy, species composition, and functioning. Different wetlands experience varying fire exposure; seasonally inundated...
Developments in the classification and nomenclature of arthropod-infecting large DNA viruses that contain pif genesNARA Subscribed
Viruses of four families of arthropod-specific, large dsDNA viruses (the nuclear arthropod large DNA viruses, or NALDVs) possess homologs of genes encoding conserved components involved in the baculovirus primary infection mechanism. The presence of such homologs encoding per os infectivity factors ( pif genes), along with their absence from other viruses and the occurrence of other shared characteristics, suggests a common or...
The annual National Conference on Health Disparities (NCHD) was launched in 2000. It unites health professionals, researchers, community leaders, and government officials, and is a catalyzing force in developing policies, research interventions, and programs that address prevention, social determinants, health disparities, and health equity. The NCHD Student Research Forum (SRF) was established in 2011 at the Medical Universit...
Coastal ecosystems are rapidly changing due to human-caused global warming, rising sea level, changing circulation patterns, sea ice loss, and acidification that in turn alter the productivity and composition of marine biological communities. In addition, regional pressures associated with growing human populations and economies result in changes in infrastructure, land use, and other development; greater extraction of fisheri...
Spatio‐temporal patterns of tree growth as related to carbon isotope fractionation in European forests under changing climateNARA Subscribed
Aim The aim was to decipher Europe‐wide spatio‐temporal patterns of forest growth dynamics and their associations with carbon isotope fractionation processes inferred from tree rings as modulated by climate warming. Location Europe and North Africa (30‒70° N, 10° W‒35° E). Time period 1901‒2003. Major taxa studied Temperate and Euro‐Siberian trees. Methods We characterize changes in the relationship between tree growth and car...
Motivation The Tundra Trait Team (TTT) database includes field‐based measurements of key traits related to plant form and function at multiple sites across the tundra biome. This dataset can be used to address theoretical questions about plant strategy and trade‐offs, trait–environment relationships and environmental filtering, and trait variation across spatial scales, to validate satellite data, and to inform Earth system mo...
Pinnipeds generally target relatively small prey that can be swallowed whole, yet often include larger prey in their diet. To eat large prey, they must first process it into pieces small enough to swallow. In this study we explored the range of prey‐processing behaviors used by Australian sea lions ( Neophoca cinerea ) when presented with large prey during captive feeding trials. The most common methods were chewing using the...