Mostafa D. Mostafa results 38
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Overweight and obesity are complicated metabolic disorders associated with negative impacts on the brain and its function, including cognitive and memory abilities. Herbal medicines are plant-based bioactive compounds produced by plants. Natural food components with antioxidant activity show promise as alternative treatments for a number of illnesses, including brain diseases. Thymoquinone (TQ) is the main bioactive constituen...
Antioxidant enzymes of Pseudochlorella pringsheimii under two stressors: variation of SOD Isoforms activityNARA Subscribed
Algae are always facing the challenge of exposure to different stress conditions, therefore raising challenges of adaptation for survival. In this context, the growth and the antioxidant enzymes of the green stress-tolerant alga Pseudochlorella pringsheimii were investigated under two environmental stresses viz. iron and salinity. The number of algal cells was moderately increased by iron treatment in the range of 0.025–0.09 m...
Brain injury and cognitive impairment are major health issues associated with neurodegenerative diseases in young and aged persons worldwide. Epigallocatechin-3-gallate (EGCG) was studied for its ability to protect against methionine (Met)-induced brain damage and cognitive dysfunction. Male mice were given Met-supplemented in drinking water to produce hyperhomocysteinemia (HHcy)-induced animals. EGCG was administered daily co...
Global meta‐analysis reveals diverse effects of microplastics on freshwater and marine fishesNARA Subscribed
Microplastic debris is a globally ubiquitous pollutant with diverse consequences for fishes, ranging from severe negative impacts to neutral, or even, positive effects. In the present study, we conducted a systematic review and meta‐analysis of experimental and observational studies to test for the impacts of microplastic exposure on freshwater, estuarine and marine fishes across diverse taxonomies, geographies, and ecosystem...
Biological indicators as tools for monitoring water quality of a hot spot area on the Egyptian Mediterranean CoastNARA Subscribed
El-Mex Bay is a semi-sheltered coastal embayment located west of Alexandria, the Egyptian Mediterranean Sea. It is considered as a hot spot area receiving industrial, agricultural, and domestic wastes from the adjacent Lake Mariut through El-Umum Drain. To evaluate the water quality of the bay, phytoplankton and macroalgae as biological tools were investigated seasonally concerning physicochemical parameters from 2018 to 2019....
A pathogenic deletion in Forkhead Box L1 (FOXL1) identifies the first otosclerosis (OTSC) geneNARA Subscribed
Otosclerosis is a bone disorder of the otic capsule and common form of late-onset hearing impairment. Considered a complex disease, little is known about its pathogenesis. Over the past 20 years, ten autosomal dominant loci ( OTSC1-10 ) have been mapped but no genes identified. Herein, we map a new OTSC locus to a 9.96 Mb region within the FOX gene cluster on 16q24.1 and identify a 15 bp coding deletion in Forkhead Box L1 co-s...