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Endothelial cell-derived microRNAs-containing extracellular vesicles and diabetic retinopathy in a mouse model of diabetesNARA Subscribed
Diabetic retinopathy (DR) is a leading cause of visual impairment and blindness in industrialized countries, resulting from diabetes mellitus. Prostaglandin E 2 (PGE 2 ), synthesized by cyclooxygenases, contributes to inflammation and apoptosis via the E-prostanoid receptor 2 (EP 2 R). Our previous studies demonstrated that EP 2 R antagonists mitigate inflammation and microvascular dysfunction in streptozotocin (STZ)-induced D...
Environmental filtering drives microbial niche shift from generalists to specialists during the aging of proglacial lakesNARA Subscribed
Global warming is altering material cycles in cryospheric and aquatic ecosystems. Accelerated glacier retreat has spurred the formation of numerous proglacial lakes, providing ideal natural laboratories for studying early ecological succession. However, the mechanisms driving microbial succession as these lakes age, particularly shifts in niche strategies and community assembly, remain poorly understood. We investigated 12 pro...
Microplastic (MP) pollution may influence aquatic greenhouse gas (GHG) emissions by altering dissolved organic matter (DOM)–microbe coupling, yet reported effects remain inconsistent across ecosystems and exposure regimes. Here, we synthesized evidence from 16 studies to quantify the net effects of MPs on CO 2 , CH 4 , and N 2 O fluxes under ambient DOM conditions. Our meta‐analysis indicates that MP exposure significantly inc...
Asymmetric nanochannels for high sensitive detection of AFB1NARA Subscribed