Key message Haplotype-based nested association mapping conducted in Australian barley identified 30 haploblocks for resistance/susceptibility to net form of net blotch. Stacking multiple resistance haplotypes significantly reduced disease severity. Abstract Net form net blotch (NFNB), caused by Pyrenophora teres f. teres , is a major fungal disease affecting barley, leading to significant yield losses globally. Improving the s...

Offshore wind turbine support structures are increasingly required to operate in deeper and more demanding marine environments, where cyclic loading, hydrodynamic forcing, corrosion, scour, soil-structure interaction, and limited long-term monitoring continue to challenge structural reliability and lifecycle performance. This review synthesizes current knowledge on the reliability, degradation mechanisms, and maintenance needs...

This study investigates the effect of bolt grade on the structural performance of T-flange joints used in wind turbine support structures. A nonlinear finite element model was developed to compare Grade 10.9 and Grade 12.9 bolts under identical loading and boundary conditions. The results showed that using Grade 12.9 bolts increased the reaction force by 12.3%, bolt stress by 21%, bolt strain by 18.7%, flange strain by 20.0%,...

Cardiotoxicity remains the leading driver of drug attrition; however, its prediction remains suboptimal when conventional hERG assays and animal models are used. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) offer a human-relevant alternative that aligns with the CiPA initiative and ICH E14/S7B guidelines. This study validated an integrated platform that combines high-purity hiPSC-CMs with Artificial I...