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Cell Biochemistry and Biophysics · 2025 · Vol. 83 · Issue 2 · Springer
Inflammatory bowel disease is a collection of intestinal disorders that cause inflammation in the digestive tract. Prolonged inflammation in the gastrointestinal tract is a major risk factor for colorectal cancer. The objective of this study was to fucus on gene expression levels of ( KRT-14 ; associated with epithelial cell integrity) and enhancer of zeste homolog-1 ( EZH-2; involved in cellular proliferation) in a IBD rat mo...
Molecular Diversity · 2022 · Vol. 26 · Issue 6 · Springer
ATP-binding cassette transporter G2 (ABCG2) is an efflux transporter related to the clinical multidrug resistance (MDR) phenomenon. Identifying ABCG2 inhibitors could help discover extraordinary curative strategies for carcinoma remediation. Hitherto, there is no medication drug inhibiting ABCG2 transporter, notwithstanding that a considerable number of drugs have been submitted to clinical-trial and investigational phases. In...