Neuroinflammation is a defining feature of acute brain injury such as acute ischemic stroke, traumatic brain injury, intracerebral hemorrhage, and subarachnoid hemorrhage, driven by complex immune interactions within the central nervous system (CNS). Among these, regulatory T cells (Tregs) have emerged as pivotal modulators that counteract the deleterious effects of effector T cell subsets, including Th1 and Th17 cells, which...