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Functional characterisation of Target of Rapamycin (TOR) signalling in PhyscomitrellaNARA Subscribed
Key message The evolutionary conserved TOR kinase positively controls growth and development of the moss Physcomitrella, development and function of its chloroplasts, its protein synthesis, and cell-cycle progression. Abstract Target of Rapamycin (TOR) is a conserved protein kinase and an important signalling hub in eukaryotes. The moss Physcomitrella ( Physcomitrium patens ) is a model organism for plant physiology, developme...
Production of human papillomavirus type 16 virus-like particles in Physcomitrella photobioreactorsNARA Subscribed
Key message First production of virus-like particles as a vaccine candidate in a non-vascular plant. Abstract Virus-like particles (VLPs) are self-assembling nanoparticles composed of viral structural proteins which mimic native virions but lack viral DNA and infectivity. VLPs are a resourceful class of biopharmaceuticals applied as subunit vaccines or as delivery vehicles for drugs and nucleic acids. Similar to viruses, VLPs...
The Kelp Forest Challenge: A collaborative global movement to protect and restore 4 million hectares of kelp forestsNARA Subscribed
Marine kelp forests cover 1/3 of our world's coastlines, are heralded as a nature-based solution to address socio-environmental issues, connect hundreds of millions of people with the ocean, and support a rich web of biodiversity throughout our oceans. But they are increasingly threatened with some areas reporting over 90% declines in kelp forest cover in living memory. Despite their importance and the threats they face, kelp...
Coastal shorelines are a key interface between terrestrial and aquatic ecosystems and are vital for human livelihood. As a result, shorelines have experienced substantial human modifications worldwide. Shoreline “hardening” – the construction of armor including seawalls, bulkheads, or rip-rap – is a common modification that has substantial negative ecological effects. Currently, restoration involving the removal of armor and r...
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