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Lipid droplets and perilipins in canine osteosarcoma. Investigations on tumor tissue, 2D and 3D cell culture modelsNARA Subscribed
Lipid droplets were identified as important players in biological processes of various tumor types. With emphasis on lipid droplet-coating proteins (perilipins, PLINs), this study intended to shed light on the presence and formation of lipid droplets in canine osteosarcoma. For this purpose, canine osteosarcoma tissue samples ( n = 11) were analyzed via immunohistochemistry and electron microscopy for lipid droplets and lipid...
Functional traits offer a rich quantitative framework for developing and testing theories in evolutionary biology, ecology and ecosystem science. However, the potential of functional traits to drive theoretical advances and refine models of global change can only be fully realised when species‐level information is complete. Here we present the AVONET dataset containing comprehensive functional trait data for all birds, includi...
Data mining and metagenomic analysis of 277 open reading frame sequences of bipartite RNA viruses of the genus Nepovirus , family Secoviridae , were performed, documenting how challenging it can be to unequivocally assign a virus to a particular species, especially those in subgroups A and C, based on some of the currently adopted taxonomic demarcation criteria. This work suggests a possible need for their amendment to accommo...
Complex interactions with nutrients and sediment alter the effects of predation on a reef‐building coralNARA Subscribed
Framework‐building corals create the three‐dimensional structure of coral reefs and are subject to predation from fishes, echinoderms, and gastropods. Anthropogenic stressors can magnify the effects of such top‐down pressure on foundation species. The gastropod Coralliophila violacea (Kiener, 1836) depletes coral energy reserves via predation, potentially increasing coral susceptibility to land‐based pollution (i.e., sediment...
Photosymbiose — neuartige Anwendungen in der BiomedizinNARA Subscribed
We have recently proposed a novel strategy named photosynthetic tissue engineering to overcome clinical problems due to hypoxia. The idea is based on transgenic photoautotrophic microorganisms that produce oxygen and at the same time secrete functional recombinant proteins into tissues. In particular, the unicellular green alga Chlamydomonas reinhardtii has successfully been used to boost the regenerative potential of several...
Journal ClubNARA Subscribed
Koi herpesvirus ( KHV ) causes KHV disease ( KHVD ). The virus is highly contagious in carp or koi and can induce a high mortality. Latency and, in some cases, a lack of signs presents a challenge for virus detection. Appropriate immunological detection methods for anti‐ KHV antibodies have not yet been fully validated for KHV . Therefore, it was developed and validated an enzyme‐linked immunosorbent assay ( ELISA ) to detect...
Holocene river and slope activity in the Visoko Basin, Bosnia‐ H erzegovina – climate and land‐use effectsNARA Subscribed
Alluvial and colluvial deposits were investigated at prehistoric tells close to the Bosna River. The chronology is based on ten radiocarbon ages, five optically stimulated luminescence ages, and on the archaeological record. Fluvial activity of the Bosna River is indicated by overbank fines [ca. 5000 (±1000) BC , 500 BC until today] and a phase of lateral displacement of the river bed with subsequent channel fills ca. 2000–500...