Climate change is affecting agricultural productivity and economic stability across many parts of the world, but small islands like Sri Lanka are more vulnerable to the effects of climate change. As a result, assessing recent rainfall dynamics is crucial for developing effective climate adaptation measures. This study analysed rainfall data from 44 meteorological stations across Sri Lanka's dry, wet and intermediate climatic z...

Rationale Early life stress (ELS) is associated with an increased risk for alcohol consumption and development of alcohol use disorder (AUD). Inflammation may be a sex-dependent link between ELS and alcohol use; however, there is limited evidence to support such an association in individuals with AUD. Methods This secondary analysis utilized cross-sectional mediation to investigate the role of peripheral inflammation in the re...

Orthologs are fundamental for enabling comparative genomics analyses that further our understanding of eukaryotic biology. The unprecedented increase in the availability of high-quality eukaryotic genomes necessitates scalable and accurate methods for orthology inference. The National Center for Biotechnology Information (NCBI) developed “NCBI Orthologs”, a resource and a computational pipeline designed to meet this challenge...

Rationale Two prominent neurobiological models of addiction, the allostatic and incentive-sensitization models, have guided clinical research on alcohol use disorder (AUD). While these models are often viewed in isolation, it is plausible these theories are complimentary. Objectives Use naturalistic, daily diary reports to determine whether positive and negative mood states influence alcohol cue sensitivity in a clinical sampl...