Summary Enterohaemorrhagic Escherichia coli (EHEC) are a subgroup of Shiga toxin‐producing E. coli that cause gastrointestinal disease with the potential for life‐threatening sequelae. Cattle serve as the natural reservoir for EHEC and outbreaks occur sporadically as a result of contaminated beef and other farming products. While certain EHEC virulence mechanisms have been extensively studied, the factors that mediate host col...