N. Sutherland results 31
· Newest (Page 1/2, per page 25)
Author: N. Sutherland ×Clear All Filters
Search Results
Environmental Niche and Species Distribution Modelling of Hawaiian Megalagrion Damselflies (Pinapinao, Odonata: Coenagrionidae)NARA Subscribed
Aim We model the ecological niches and geographic distributions of 22 of 23 Megalagrion damselfly species and explore ecological and evolutionary hypotheses that may explain patterns of diversity. Location The Hawaiian Archipelago (Kaua‘i, O‘ahu, Moloka‘i, Lāna‘i, Maui, Hawai‘i). Taxon Megalagrion damselflies (Odonata: Coenagrionidae) are an endemic Hawaiian radiation of 23 species. Methods We gathered occurrence data from GBI...
Chitinase-like proteins (CLPs) are of wide interest due to their significant roles during both homeostatic and pathological processes. Human CLPs such as YKL-40 have been proposed as biomarkers of disease severity in many conditions. Murine CLPs Brp39, Ym1, and Ym2 are similarly upregulated in multiple mouse models of pathology. Investigation of Ym1 and Ym2 is hampered by recent gene duplication events on the C57BL/6, but not...
Industrialized environments, despite benefits such as higher levels of formal education and lower rates of infections, can also have pernicious impacts upon brain atrophy. Partly for this reason, comparing age-related brain volume trajectories between industrialized and non-industrialized populations can help to suggest lifestyle correlates of brain health. The Tsimane, indigenous to the Bolivian Amazon, derive their subsisten...
The transposable element-derived transcript of LIN28B has a placental origin and is not specific to tumoursNARA Subscribed
Transposable elements (TEs) are genetic elements that have evolved as crucial regulators of human development and cancer, functioning as both genes and regulatory elements. When TEs become dysregulated in cancer cells, they can serve as alternate promoters to activate oncogenes, a process known as onco-exaptation. This study aimed to explore the expression and epigenetic regulation of onco-exaptation events in early human deve...
Investigation of Mitochondrial Related Variants in a Cerebral Small Vessel Disease CohortNARA Subscribed
Monogenic forms of cerebral small vessel disease (CSVD) can be caused by both variants in nuclear DNA and mitochondrial DNA (mtDNA). Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) is known to have a phenotype similar to Cerebral Autosomal Dominant Arteriopathy with Sub-cortical Infarcts and Leukoencephalopathy (CADASIL), and can be caused by variants in the mitochondrial genome and in several n...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
With the accelerating pace of global change, it is imperative that we obtain rapid inventories of the status and distribution of wildlife for ecological inferences and conservation planning. To address this challenge, we launched the SNAPSHOT USA project, a collaborative survey of terrestrial wildlife populations using camera traps across the United States. For our first annual survey, we compiled data across all 50 states dur...
Resilience in moving water: Effects of turbulence on the predatory impact of the lobate ctenophore Mnemiopsis leidyiNARA Subscribed
Despite its delicate morphology, the lobate ctenophore Mnemiopsis leidyi thrives in coastal ecosystems as an influential zooplankton predator. Coastal ecosystems are often characterized as energetic systems with high levels of natural turbulence in the water column. To understand how natural wind‐driven turbulence affects the feeding ecology of M. leidyi , we used a combination of approaches to quantify how naturally and labor...
Using massively parallel sequencing data from two species with different life history traits, American lobster ( Homarus americanus ) and Arctic Char ( Salvelinus alpinus ), we highlight how an unbalanced sex ratio in the samples and a few sex‐linked markers may lead to false interpretations of population structure and thus to potentially erroneous management recommendations. Here, multivariate analyses revealed two genetic cl...
Migration is a ubiquitous life history trait with profound evolutionary and ecological consequences. Recent developments in telemetry and genomics, when combined, can bring significant insights on the migratory ecology of nonmodel organisms in the wild. Here, we used this integrative approach to document dispersal, gene flow and potential for local adaptation in anadromous Arctic Char from six rivers in the Canadian Arctic. Ac...
Prioritization of knowledge needs for sustainable aquaculture: a national and global perspectiveNARA Subscribed
Aquaculture is currently the fastest expanding global animal food production sector and is a key future contributor to food security. An increase in food security will be dependent upon the development and improvement of sustainable practices. A prioritization exercise was undertaken, focusing on the future knowledge needs to underpin UK sustainable aquaculture (both domestic and imported products) using a ‘task force’ group o...
Pramipexole effects on startle gating in rats and normal menNARA Subscribed
One Hundred Questions of Importance to the Conservation of Global Biological DiversityNARA Subscribed
We identified 100 scientific questions that, if answered, would have the greatest impact on conservation practice and policy. Representatives from 21 international organizations, regional sections and working groups of the Society for Conservation Biology, and 12 academics, from all continents except Antarctica, compiled 2291 questions of relevance to conservation of biological diversity worldwide. The questions were gathered...