Telomere length (TL) has been proposed as a marker of appendicular lean mass (ALM) decline; however, longitudinal evidence remains limited. We aimed to investigate the longitudinal association between TL and 6-year trajectories of ALM. This longitudinal study included 185 older adults aged 55–75 years with overweight or obesity and metabolic syndrome at baseline. Baseline TL was assessed using a monochrome multiplex real-time...

Occupational exposure to metal(loid)s in petrochemical industries has raised concerns about possible effects on male reproductive health. This study examines the link between metal(loid) exposure and semen quality parameters among petrochemical workers (PWs) compared to a non-petrochemical control group, using the WHO 2021 reference values as a standard. A cross-sectional analysis was performed on 176 healthy individuals, cons...

The protective role of dietary vitamin D intake on cognitive function is of interest, but evidence remains inconsistent. We aimed to evaluate the association between dietary vitamin D intake and 2-year cognitive changes in older adults at risk of cognitive decline. This longitudinal study comprised 5454 individuals (aged 55–75 years in men and 60–75 years in women) who exhibited overweight/obesity and metabolic syndrome. Data...

Cognitive impairment is present in a broad spectrum of medical conditions and in aging. Here, we aimed to identify plasma proteins related to cognitive function in a sample of older adults with overweight/obesity and metabolic syndrome. A total of 129 subjects (mean age 64.7 years; 36% females) were grouped according to low (l-GCF, N =65) or high (h-GCF, N =64) global cognitive function and matched according to education, sex,...