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Archives of Toxicology1
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Neel Deferm results 4 · Newest (Page 1/1, per page 25)
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Gastrointestinal Bile Salt Concentrations in Healthy Adults Under Fasted and Fed Conditions: A Systematic Review and Meta-Analysis for Mechanistic Physiologically-Based Pharmacokinetic (PBPK) ModellingNARA Subscribed
The AAPS Journal · 2025 · Vol. 27 · Issue 1 · Springer
Laura G. Al-Amiry Santos; Helen Musther; Neeru Bala; Neel Deferm; Gaurangkumar Patel; Joachim Brouwers; David B. Turner
Bile salts are biosurfactants released into the intestinal lumen which play an important role in the solubilisation of fats and certain drugs. Their concentrations vary along the gastrointestinal tract (GIT). This is significant for implementation in physiologically based pharmacokinetic (PBPK) modelling to mechanistically capture drug absorption. The aims of this meta-analysis were to collate all appropriate data on intestina...
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Unravelling the Hepatic Elimination Mechanisms of ColistinNARA Subscribed
Pharmaceutical Research · 2023 · Vol. 40 · Issue 7 · Springer
Bing Qi; Matthias Gijsen; Tom De Vocht; Neel Deferm; Pieter Van Brantegem; Getahun B. Abza; Nina Nauwelaerts; Joost Wauters; Isabel Spriet; Pieter Annaert
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Mechanisms and in vitro models of drug-induced cholestasisNARA Subscribed
Archives of Toxicology · 2019 · Vol. 93 · Issue 5 · Springer
Eva Gijbels; Vânia Vilas-Boas; Neel Deferm; Lindsey Devisscher; Hartmut Jaeschke; Pieter Annaert; Mathieu Vinken
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Effect of Cryopreservation on Enzyme and Transporter Activities in Suspended and Sandwich Cultured Rat HepatocytesNARA Subscribed
The AAPS Journal · 2018 · Vol. 20 · Issue 2 · Springer
Janneke Keemink; Neel Deferm; Tom De Bruyn; Patrick Augustijns; Thomas Bouillon; Pieter Annaert
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