Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) that typically requires long-term drug treatment. The emerging role of glucagon-like peptide 1 (GLP-1) and its receptor agonists in gastrointestinal diseases has drawn much attention. A mouse model of acute colitis was conducted using a 7-day protocol of dextran sulfate sodium (DSS, 3% w/v in drinking water) administration. The efficacy of liraglutide (a GLP...

Phenylethanoid glycosides are naturally occurring water-soluble molecules with remarkable biological characteristics that are abundant throughout the plant world. Acteoside (AC) is a phenylethanoid glycoside that was first discovered in mullein, but is also found in various other plant species. It has four moieties: caffeic acid, glucose, rhamnose, and phenylethyl alcohol. AC is an important bioactive natural compound isolated...

Across diverse cultures, herbal remedies have been used to alleviate oral discomfort and maintain dental hygiene. This review presents studies on herbal remedies with remarkable antimicrobial, anti-inflammatory, antioxidant, anticancer, anticaries, analgesic, and healing properties. The manuscripts demonstrate the depth of scientific inquiry into herbal remedies used for the management of various oral and dental health conditi...

Rationale Risperidone is the first antipsychotic to be approved by Food and Drug Administration (FDA) for treating autism spectrum disorder (ASD). The potential efficacy of metformin in preventing and/or controlling ASD behavioral deficits was also recently reported. Suppression of hippocampus autophagy was suggested as a potential pathologic mechanism in ASD. Objectives Is metformin’s ability to improve ASD clinical phenotype...