Neil J Hewitt results 14
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Efficiency of working coveralls and chemical resistant gloves in reducing operator exposure to pesticidesNARA Subscribed
Personal Protective Equipment (PPE) is used to reduce exposure when working with chemicals. For pesticides, exposure scenarios comprise mixing and loading (M&L) and application. The exposure prediction model recommended by European regulatory agencies for operator risk assessments—the Agricultural Operator Exposure Model (AOEM) – is based on 48 operator exposure studies involving over 500 professional operators from 10 Europea...
Minimizing operator exposure: field data analysis of three closed transfer systems for pesticide mixing and loadingNARA Subscribed
Three Closed Transfer Systems (CTS) were evaluated for their reduction of operator exposure to plant protection products during mixing and loading: the inverted extraction systems, easyFlow M and easyconnect, and the probe extraction system, GoatThroat ® . Exposure data were generated for gloves, hands, head, inner and outer body dosimeters generated in 4 European countries for high rate (Sorbitol) and low rate (Xylitol) surro...
Root aphid (Aploneura lentisci) population size on perennial ryegrass is determined by drought and endophyte strainNARA Subscribed
Climate change is anticipated to lead to an increase in the occurrence and intensity of drought and fluctuations in insect cycles that will challenge modern pasture systems. Feeding by root aphids such as Aploneura lentisci Pass. can be a significant challenge to pastures. These below-ground living aphids are commonly found in New Zealand and Australia, feeding year-round on the roots of graminaceous plants such as perennial r...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
Design and development of a new ambr250® bioreactor vessel for improved cell and gene therapy applicationsNARA Subscribed
The emergence of cell and gene therapies has generated significant interest in their clinical and commercial potential. However, these therapies are prohibitively expensive to manufacture and can require extensive time for development due to our limited process knowledge and understanding. The automated ambr250® stirred-tank bioreactor platform provides an effective platform for high-throughput process development. However, th...
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