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The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
Waterfowl Move Less in Heterogeneous and Human‐Populated Landscapes, With Implications for Spread of Avian Influenza VirusesNARA Subscribed
Animal movements contribute to the spread of infectious diseases and are driven in part by environmental conditions. We investigated the links among the environment, animal movement, and infectious disease dynamics in waterfowl, which are among the primary wildlife hosts of avian influenza viruses. By combining telemetry data on 4606 individuals from 26 waterfowl species with data on land cover, weather, and vegetation, we fou...
Quantifying intra-urban socio-economic and environmental vulnerability to extreme heat events in Johannesburg, South AfricaNARA Subscribed
Urban populations face increasing vulnerability to extreme heat events, particularly in rapidly urbanising Global South cities where environmental exposure intersects with socioeconomic inequality and limited healthcare access. This study quantifies heat vulnerability across Johannesburg, South Africa, by integrating high-resolution environmental data with socio-economic and health metrics across 135 urban wards. We examine ho...
Mapping illegal trade routes of live cheetahs from the Horn of Africa to the Arabian PeninsulaNARA Subscribed
Less than 7000 cheetahs ( Acinonyx jubatus ) persist in Africa. Although human–wildlife conflict, habitat degradation, and loss of prey are major threats to cheetah populations, illegal trade in live cubs for pets may have the most significant impact on populations in the Horn of Africa. We developed a novel, stepwise decision support tool to predict probable trafficking routes by leveraging the power of distinct modeling appr...
The Toxicology Investigators Consortium 2023 Annual ReportNARA Subscribed
The Toxicology Investigators Consortium 2022 Annual ReportNARA Subscribed
In order to make progress towards Sustainable Development Goal 2 – Zero Hunger - we must acquire a better understanding of what continues to hamper achieving food security, particularly in contexts where progress has been achieved, but has then faltered. This article investigates access to nutrition and food services in three of the Indian state of Odisha’s traditionally poorer districts, where a large number of the state’s mo...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
Insect phenological lability is key for determining which species will adapt under environmental change. However, little is known about when adult insect activity terminates and overall activity duration. We used community‐science and museum specimen data to investigate the effects of climate and urbanisation on timing of adult insect activity for 101 species varying in life history traits. We found detritivores and species wi...
Our ability to completely and repeatedly map natural environments at a global scale have increased significantly over the past decade. These advances are from delivery of a range of on-line global satellite image archives and global-scale processing capabilities, along with improved spatial and temporal resolution satellite imagery. The ability to accurately train and validate these global scale-mapping programs from what we w...
Sharing and reporting benefits from biodiversity researchNARA Subscribed
Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred miceNARA Subscribed
Modulation of the ageing process by dietary restriction (DR) across multiple taxa is well established. While the exact mechanism through which DR acts remains elusive, the gasotransmitter hydrogen sulphide (H 2 S) may play an important role. We employed a comparative-type approach using females from three ILSXISS recombinant inbred mouse strains previously reported to show differential lifespan responses following 40% DR. Foll...
The brain represents the space immediately surrounding the body differently to more distant parts of space. Direct evidence for this ‘peripersonal space’ representation comes from neurophysiological studies in monkeys, which show distance-dependent responses to visual stimuli in neurons with spatially coincident tactile responses. Most evidence for peripersonal space in humans is indirect: spatial- and distance-dependent modul...