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Pharmaceutical Research · 2023 · Vol. 40 · Issue 11 · Springer
Background While the majority of patients with atopic dermatitis (AD) achieve disease control with dupilumab treatment, there is variability in which patients achieve clear disease. The predictors of these responses are currently unclear. Integrated models were developed to evaluate the exposure–response (E-R) relationship of dupilumab in children, adolescents, and adults with AD. Methods Data from six Phase II and III clinica...