Acid-sensing ion channels (ASICs) are proton-gated members of the degenerin/epithelial sodium channel family that are emerging as multifaceted regulators of cardiovascular function. ASICs expressed in baroreceptor, cardiac, and skeletal muscle afferents contribute to reflex control of blood pressure, cardiac function, and sympathetic outflow. In vascular smooth muscle and endothelial cells, ASICs integrate mechanical, metaboli...

Dryland ecosystems cover 41% of Earth's land surfaces, account for 44% of cultivated lands and 60% of food sources, and make large contributions to the global water and carbon cycles. However, these ecosystems are experiencing unprecedented extremes including heatwaves, floods, and droughts as well as hotter temperatures and often declining water resource availability. These ecosystems are some of the most challenging to monit...

Marine invertebrates, which comprise 92% of ocean biodiversity, play a crucial role in maintaining healthy and productive ecosystems by shaping habitats and forming part of the foundation of food webs. They also serve as a critical food source sustaining major global fisheries and provide valuable models for biomedical research due to their diverse physiological adaptations. Climate change-driven biodiversity loss threatens bo...

As reef-building coral cover has declined worldwide, coral restoration has become a widespread response towards repopulating degraded reefs. In-situ nurseries have provided refugia for the regrowth of several coral species, yet long-term success following outplanting remains highly variable, particularly when corals are introduced into novel or marginal environments. Additionally, while growth and survivorship are commonly use...

Indigenous knowledge systems have some of the most comprehensive bodies of information about the nature of climate change and about how to take action to avert dangerous climate change. The inclusion of Indigenous knowledge systems and Indigenous scholars in major scientific assessments is widely advocated for today. However, little is understood about the history of how Indigenous persons have influenced scientific assessment...

Protists are widely distributed, single‐celled eukaryotes whose hidden diversity has increasingly been revealed through molecular techniques. Despite this progress, global studies remain uneven, with Southeast Asia, particularly the Philippines, understudied. This research investigates protist community diversity, including Amoebozoa as a focal subgroup, across freshwater and marine ecosystems using a metabarcoding approach su...

Climate change threatens biodiversity when species cannot tolerate, adapt to, or track shifting environmental conditions to stay within their climatic niches. A major unresolved question is whether and how species' genetic diversity modulates these dynamics, buffering against range contractions or facilitating range expansions. To test this, we integrated the largest global databases of species range shifts and genetic diversi...

Benthic grazers and suspension feeders, such as oysters and mussels, may play a disproportionate role in controlling algal biomass and plankton community composition in estuarine systems. Nonetheless, their effects on plankton communities remain poorly understood across environmental contexts, in part from a paucity of in situ measurements. Here, we conducted in situ manipulative field experiments to evaluate the effects of th...

Purpose This study aimed to identify provider- and practice-level factors influencing human papillomavirus (HPV) vaccine uptake among Chinese American (CA) adolescents. Despite increasing public health efforts, HPV vaccination rates in this population remain suboptimal, and knowledge on the link between provider/practice characteristics and vaccine uptake is limited. Methods We analyzed data from 1,272 CA adolescents (aged 13–...