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Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
For the first time, this study reports the content of tropane alkaloids (TAs) in soybean and soymeal samples sourced from 13 different countries, as well as in various cereals (including corn, millet, wheat, and sorghum) and a product (Super Cereals). The analysis was conducted using a fully validated solid-liquid extraction (SLE) with dilute-and-shoot (DnS) method along with a liquid chromatography-tandem mass spectrometry (L...
Nature-based solutions may be applied to restore or enhance coastal ecosystem function but should be considered carefully within the context of sediment transport that drives morphological change. This study, for the first time, assesses rates of sediment transport and deposition at a managed dyke realignment site in the critical time period immediately following the dyke breach and before the establishment of salt marsh veget...
Marine Ecosystem-Based Management (EBM) approaches are a well-established and fundamental component of international agreements and treaties, regional seas conventions, assessment strategies, European Directives and national and regional instruments. However, there is the need to interrogate and clarify the implementation of EBM approaches under current marine management. Although particular focus here is within the European U...
Anadromous salmonids migrate seaward to exploit feeding and growth opportunities in marine habitats, yet how smolt biological characteristics influence their marine migratory behavior remains poorly understood. This study used 9 years of trout ( Salmo trutta ) population monitoring data from 15,595 tagged age‐0+ parr, 1033 smolts detected migrating downstream in spring, and 99 adults detected returning from their first marine...
Bioanalytical Method Comparison Strategy for Clinical Anti-drug Antibody ImmunoassaysNARA Subscribed
Per FDA guidance, method comparability should be established if an anti-drug antibody (ADA) assay is run by two or more independent laboratories during a study. Genentech, Inc. is evaluating an immunogenicity risk-based comparability approach consisting of both technical and clinical aspects. Technical comparability of the relative sensitivity (RS) is assessed using the Two One-Sided T-tests (TOST) statistical analysis which e...
Alternate wetting and drying: a water-saving technology for sustainable rice production in Burkina Faso?NARA Subscribed
With emerging water scarcity and rising fertilizer prices, optimising future water use while maintaining yield and nutrient efficiency in irrigated rice is crucial. Alternate wetting and moderate soil drying irrigation (i.e., re-irrigation when the water level reaches 15 cm below the soil surface) has proven to be an efficient water-saving technology in semi-arid zones of West Africa, reducing water inputs without yield penalt...