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Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
Dietary niches of endemic and range-expanding salmonids in the western Canadian ArcticNARA Subscribed
The cumulative effects of climate change are impacting Arctic species and facilitating increased interactions between Arctic and sub-Arctic species. Anadromous Arctic char Salvelinus alpinus and the northern Dolly Varden Salvelinus malma malma are endemic Arctic fishes vulnerable to the impacts of climate change, yet our understanding of the dietary niches they occupy is limited. The recent increased occurrence of sub-Arctic P...
Voxel-wise insights into early Alzheimer’s disease pathology progression: the association with APOE and memory declineNARA Subscribed
Longitudinal investigation of the Apolipoprotein E (APOE) genotype’s impact on Alzheimer’s disease (AD) biomarker progression, focusing on amyloid beta (Aβ) accumulation and gray matter (GM) atrophy, integrating cognitive decline and baseline levels. Longitudinal florbetapir-PET and T1-weighted MRI data from 100 cognitively normal (CN) and mild cognitive impaired (MCI) participants both with considerable global Aβ accumulation...
Complementary value of molecular, phenotypic, and functional aging biomarkers in dementia predictionNARA Subscribed
DNA methylation age (MA), brain age (BA), and frailty index (FI) are putative aging biomarkers linked to dementia risk. We investigated their relationship and combined potential for prediction of cognitive impairment and future dementia risk using the ADNI database. Of several MA algorithms, DunedinPACE and GrimAge2, associated with memory, were combined in a composite MA alongside BA and a data-driven FI in predictive analyse...
Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volumeNARA Subscribed
The concept of age acceleration, the difference between biological age and chronological age, is of growing interest, particularly with respect to age-related disorders, such as Alzheimer’s Disease (AD). Whilst studies have reported associations with AD risk and related phenotypes, there remains a lack of consensus on these associations. Here we aimed to comprehensively investigate the relationship between five recognised meas...
Testing a global standard for quantifying species recovery and assessing conservation impactNARA Subscribed
Recognizing the imperative to evaluate species recovery and conservation impact, in 2012 the International Union for Conservation of Nature (IUCN) called for development of a “Green List of Species” (now the IUCN Green Status of Species). A draft Green Status framework for assessing species’ progress toward recovery, published in 2018, proposed 2 separate but interlinked components: a standardized method (i.e., measurement aga...
The Mandalovoo–Gurvansayhan terranes in the southern Gobi of Mongolia: new insights from the Bayankhoshuu Ruins sectionNARA Subscribed
The Bayankhoshuu Ruins section in southern Mongolia is characterized by strongly thrusted and folded sequences. Overall, three sections ranging from Ordovician to Carboniferous rocks were studied. Facies analysis combined with stratigraphic data provide improved lithostratigraphic descriptions of Palaeozoic successions in the Mushgai region. The overall marine sedimentary sequence is punctuated by volcanic rocks – basaltic lav...
The Hushoot Shiveetiin gol section (Baruunhuurai Terrane, Mongolia): sedimentology and facies from a Late Devonian island arc settingNARA Subscribed
A Late Devonian to (?)Early Mississippian section at Hushoot Shiveetiin gol in the Baruunhuurai Terrane of the Central Asian Orogenic Belt (CAOB) exposes large parts of cyclic Famennian shallow-water siliciclastic shelf deposits composed of siltstones, sandstones, shales, volcaniclastics, and intercalated autochthonous carbonates. The youngest part of the section, possibly Early Mississippian, is represented by arkosic sandsto...