P. Du results 192
· Newest (Page 1/8, per page 25)
Author: P. Du ×Clear All Filters
Search Results
Interest in the P2Y6 receptor (P2Y6R) has increased substantially over the past decade, driven by evidence that pharmacological inhibition is beneficial in neurodegenerative disease models, inflammatory pathologies, and cancer. However, therapeutic targeting of the P2Y6R has remained a challenge due to a lack of available drug-like molecules. In 2023 and 2024, benzimidazole and quinoline chemotypes respectively, were reported...
Precision measurement of the Ds*+-Ds+ meson mass differenceNARA Subscribed
Morphological plasticity of endophytic Chitinophaga pinensisNARA Subscribed
Environmental changes, whether due to climate change or human influences, compromise the resilience of plants to biotic and abiotic stresses, such as pathogens, drought and heat. Plant microbiota are known to promote plant resilience. To be able to harness the power of the plant microbiome we need to identify microbiota with health-promoting properties. Recent studies have demonstrated that the bacterium Chitinophaga pinensis...
Neurobiology of co-morbid stress and a western diet in mice: mitochondrial, proteomic and behavioral outcomesNARA Subscribed
Chronic stress (CS) and hyper-caloric diets promote affective disorders, however pathobiological interactions await definition. Neurobiological and behavioral influences of chronic stress (CS; 2 h/day restraint for 2 wks) were studied in male C57Bl/6 mice fed a control diet (CD; 12% kcal as fat/65% carbohydrate/23% protein) or Western diet (WD; 32% kcal fat/57% carbohydrate/11% protein) for 20 wks. CS induced weight loss and a...
Phthorimaea ( Tuta ) absoluta (Meyrick) (Lepidoptera: Gelechiidae), commonly known as the South American leafminer, was first detected in South Africa in 2016. Its resistance to various insecticides in multiple countries underscores the urgent need for integrated pest management (IPM) strategies. Entomopathogenic nematodes (EPNs), traditionally used against soil-dwelling pests, are receiving increasing attention for foliar app...
Numerical Analysis of Triaxial Tests for Interpreting Sample Stiffness with Existing Measurement SystemsNARA Subscribed
This paper presents the first systematic numerical study employing a realistic elasto-plastic non-linear soil model to examine factors affecting the measurement of soil stiffness at low to intermediate strains in the triaxial apparatus. The study is motivated by the development of new image-based measurement techniques for triaxial testing. The results from numerical simulations are presented that quantify the influence on sam...
Motivation Here, we make available a second version of the BioTIME database, which compiles records of abundance estimates for species in sample events of ecological assemblages through time. The updated version expands version 1.0 of the database by doubling the number of studies and includes substantial additional curation to the taxonomic accuracy of the records, as well as the metadata. Moreover, we now provide an R packag...