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Mixed effect estimation in deep compartment models: Variational methods outperform first-order approximationsNARA Subscribed
This work focusses on extending the deep compartment model (DCM) framework to the estimation of mixed-effects. By introducing random effects, model predictions can be personalized based on drug measurements, enabling the testing of different treatment schedules on an individual basis. The performance of classical first-order (FO and FOCE) and machine learning based variational inference (VI) algorithms were compared in a simul...
Tide–surge interaction plays a substantial role in determining the characteristics of coastal water levels over shallow regions. We study the tide–surge interaction observed at seven tide gauges along Singapore and the east coast of Peninsular Malaysia, focusing on the timing of extreme non-tidal residuals relative to tidal high water. We propose a modified statistical framework using a no-tide–surge interaction (no-TSI) null...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Grey seals ( Halichoerus grypus ) are a qualifying feature of three special areas of conservation (SACs) in Wales, yet relatively little is known of their site use along this coastline. Since 1992, many individuals and organisations have contributed to a grey seal photographic identification database held by Natural Resources Wales, which is one of the largest and oldest of its kind, providing key information from grey seal ha...
Mineral nutrition and bone health in salmonidsNARA Subscribed
In the recent years, challenges faced in salmonid farming with regard to deformities have helped to improve our knowledge on skeletal biology and development of bone health in salmonids. Different nutritional, genetic and environmental factors are associated with skeletal deformities in salmonids and other fish species. Minerals are a group of essential nutrients having a vital role to play in skeletal development, growth and...
The diurnal cycle of marine cloud feedback in climate modelsNARA Subscribed
Maladaptation and phenotypic mismatch in hatchery‐reared Atlantic salmon Salmo salar released in the wildNARA Subscribed
Changes in body shape, fluctuating asymmetry ( FA ) and crypsis were compared among Atlantic salmon Salmo salar fry kept as controls in captivity and those released and subsequently recaptured in the wild according to a before‐after‐control‐impact ( BACI ) design. Hatchery fish that survived in the wild became more cryptic and displayed a much lower incidence of fin erosion and of asymmetric individuals than control fish kept...
Vegetable oils (Vo) are an alternative to fish oil (Fo) in aquaculture feeds. This study aimed to evaluate the effect of dietary soybean oil (Vo diet), rich in linoleic acid, and of dietary fish oil (Fo diet) on the development of spinal deformities under bacterial lipopolysaccharide (LPS)‐induced chronic inflammation conditions in Atlantic salmon, Salmo salar L. Fish [25 g body weight (BW)] were fed the experimental diets for...
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