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NARA Subscribed1
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Springer Nature1
Journal
Angiogenesis1
Publication Year
20241
P. Machillot results 1 · Newest (Page 1/1, per page 25)
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Author: P. Machillot ×Clear All Filters
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Impact of heterozygous ALK1 mutations on the transcriptomic response to BMP9 and BMP10 in endothelial cells from hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension donorsNARA Subscribed
Angiogenesis · 2024 · Vol. 27 · Issue 2 · Springer
T. Al Tabosh; H. Liu; D. Koça; M. Al Tarrass; L. Tu; S. Giraud; L. Delagrange; M. Beaudoin; S. Rivière; V. Grobost; M. Rondeau-Lutz; O. Dupuis; N. Ricard; E. Tillet; P. Machillot; A. Salomon; C. Picart; C. Battail; S. Dupuis-Girod; C. Guignabert; A. Desroches-Castan; S. Bailly
Heterozygous activin receptor-like kinase 1 ( ALK1 ) mutations are associated with two vascular diseases: hereditary hemorrhagic telangiectasia (HHT) and more rarely pulmonary arterial hypertension (PAH). Here, we aimed to understand the impact of ALK1 mutations on BMP9 and BMP10 transcriptomic responses in endothelial cells. Endothelial colony-forming cells (ECFCs) and microvascular endothelial cells (HMVECs) carrying loss of...
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