P. Moran results 106
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Correlation between DNA methylation and transcriptomic changes in golden Asian sea bass ( Lates calcarifer ): An integrated approachNARA Subscribed
Lates calcarifer , commonly known as barramundi perch, Asian sea bass or barramundi, is a significant aquaculture species across the Indo‐Pacific. Barramundi typically exhibit a silver to bronze wild‐type (WT) skin colour, with occasional golden (xanthic) variants of commercial interest. Although previous studies have identified gene expression differences between golden and WT variants, the genetic mechanism driving golden co...
Genes flbA-E are involved in sporulation and vegetative growth in Aspergillus nidulans. Inactivation of either of these genes results in a fluffy phenotype with delayed or even abolished sporulation. Previously, a non-sporulating phenotype was obtained by inactivating flbA in Aspergillus niger, which was accompanied by lysis, thinner cell walls, and an increased secretome complexity. Here, we further studied the role of the fl...
Whole‐Genome Resequencing Reveals Polygenic Signatures of Directional and Balancing Selection on Alternative Migratory Life HistoriesNARA Subscribed
Migration in animals and associated adaptations to contrasting environments are underpinned by complex genetic architecture. Here, we explore the genomic basis of facultative anadromy in brown trout ( Salmo trutta ), wherein some individuals migrate to sea while others remain resident in natal rivers, to better understand how alternative migratory tactics (AMTs) are maintained evolutionarily. To identify genomic variants assoc...
Aspergillus niger is widely used as a cell factory for the industrial production of enzymes. Previously, it was shown that deletion of α-1–3 glucan synthase genes results in smaller micro-colonies in liquid cultures of Aspergillus nidulans . Also, it has been shown that small wild-type Aspergillus niger micro-colonies secrete more protein than large mirco-colonies. We here assessed whether deletion of the agsC or agsE α-1–3 gl...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Uncovering which biogeochemical processes have a critical role controlling dissolved organic matter (DOM) compositional changes in complex estuarine environments remains a challenge. In this context, the aim of this study is to characterize the dominant patterns of variability modifying the DOM composition in an estuary off the Southeastern U.S. We collected water samples during three seasons (July and October 2014 and April 2...
Bacterial responses to background organic pollutants in the northeast subarctic Pacific OceanNARA Subscribed
Summary Thousands of man‐made synthetic chemicals are released to oceans and compose the anthropogenic dissolved organic carbon (ADOC). Little is known about the effects of this chronic pollution on marine microbiome activities. In this study, we measured the pollution level at three sites in the Northeast Subarctic Pacific Ocean (NESAP) and investigated how mixtures of three model families of ADOC at different environmentally...
The jury is still out regarding the generality of adaptive ‘transgenerational’ effectsNARA Subscribed
A recent meta‐analysis concluded, ‘ transgenerational effects are widespread, strong and persistent’ . We identify biases in the literature search, data and analyses, questioning that conclusion. Re‐analyses indicate few studies actually tested transgenerational effects – making it challenging to disentangle condition‐transfer from anticipatory parental effects, and providing little insight into the underlying mechanisms.